What can result from a highly tolerant subject when exposed to an irritant agent?

A highly tolerant subject typically exhibits a reduced physiological response to irritant agents due to their body’s adaptation or acclimatization to such substances. This means that repeated exposure might lead the subject to perceive the irritants less acutely, resulting in a diminished reaction. Consequently, rather than experiencing overwhelming distress or incapacitation, they may maintain a level of functionality that allows them to remain composed or able to resist the effects of the irritant. This concept is critical in understanding how various individuals may react differently to the same stimuli based on their previous experiences and adaptations, which can inform how law enforcement or security personnel approach interactions with individuals who may be highly tolerant to certain agents.